As pet owners, we always want our pet to receive the highest quality veterinary care when the situation requires it.
Nowadays veterinarians understand that pet owners are well-informed and have very high expectations for improving their companion's health.
Why should you consider preparing a personalized/compounding veterinary treatment as a solution to your pet's medical problems?
And the answer...may be another question: ""How difficult is it to get your cat to swallow a pill?"
Modern pharmaceutical preparation techniques (compounding) are becoming a very good solution to veterinary problems - they represent the science and, at the same time, the art of compounding treatments for animals.
The development of veterinary compounding in recent years has brought significant benefits to owners. Pets often suffer from variations of the same diseases that humans can have, including skin rashes, eye and ear infections, heart disease, cancer, and diabetes.
However, pet medication also presents certain particularities that can be solved with the help of personalized/compounding pharmaceutical preparations.
- It's well known amongst pet owners, that animals can be extremely difficult to treat with medication. Cats are notorious for their stubbornness and refusal to swallow pills, for example.
- Dosages can also be very complicated for dogs - a dose of medication that works for a 30- kilogram Golden Retriever may be far too high for a 2- kilogram Yorkshire Terrier.
Veterinary pharmaceutical compounding allows the wishes regarding the pet's health, shared by doctors, as well as the owner, to be fulfilled through personalized treatments, perfectly adapted to the particularities of each patient.
For successful veterinary treatment, the doctor's concerns include:
The dosing of standardized animal medicines can be difficult for the owner, especially if small amounts are needed or if the recommended dose to be administered is difficult to obtain from the concentration that is commercially available.
In the case of substances with a limited therapeutic index, an approximation, a "rounding" to the nearest measurable division, can lead to toxic levels or overdoses.
Customized laboratory preparations allow for obtaining adequate concentrations of active substances, thus achieving precise dosages, which minimize the occurrence of adverse reactions and accidental overdose phenomena. Titration of high-concentration substances by a pharmacist who is well versed in pharmaceutical preparation techniques allows for modification of doses so that they can be easily manipulated and administered with precision by the owner.
Like their owners, pets are unique. They come in all shapes, sizes, ages, and breeds, and may be sensitive to certain ingredients, such as lactose. As a result, not all over-the-counter medications are suitable for use.
In this situation, the veterinarian may recommend a dedicated preparation in the form of a flavored syrup, with another dosage form having the required amount of active substance.
From time to time, a manufacturer may discontinue the production of a particular veterinary drug. Often, this is because it is not in demand in large enough quantities to be cost-effective to produce. When a particular serial product has had beneficial effects on animals and is no longer available, upon the recommendation of the veterinarian, the pharmacist may compound a preparation for the necessary therapy (he may adapt the concentration, dosage form and flavor to the specific needs of the animal).
In conclusion, for the success of a veterinary treatment, it is very important that the relationship between the veterinarian, owner and pharmacist is very good. The quality of the pharmaceutical compounding process also matters a lot.
In the Crisia Pharmacy laboratory, we use high-purity active ingredients and modern incorporation bases to prepare various formulas for veterinary use.
Personalized preparations used in the treatment of various veterinary pathologies can only be dispensed based on a prescription recommended by a doctor.
* Veterinary compounding medicine used in the treatment of various pathologies are only available on the basis of a doctor's prescription.
Pharmaceutical forms for veterinary use compounded in the Crisia Farm laboratory:
- capsules
- oral suspensions
- topically administered preparations
- transdermal preparations
- thermoreversible gels
- oral pastes
- powders
- medicine in the form of treats
To accurately fill the capsules, respecting the exact dosage of the medication recommended by the veterinarian, in the Crisia Pharmacy recipe we use capsules of different sizes.
A powder treatment is thus prepared for administration in a small, individual gelatinous package, unflavored, easy to swallow and which masks any bitter taste. The size of the capsules depends on the concentration of the drug and the particularities of the patient, to make administration easier and more effective for both the animal and the owner.
Flavored suspensions are an excellent form of drug administration. The solubility of the drug is what determines the difference between a suspension and a solution.
If a substance is insoluble and still stable in a liquid, it can be prepared as a suspension. This process allows for uniform dispersion of the active substance throughout the vehicle, as well as precise dosing. If a formula is soluble and stable in a liquid, it is prepared in a solution. When compounding, the stability of the composition, homogeneity, but also the change in pH will be taken into account.
The Crisia Farm Laboratory compounds creams, lotions, gels, solutions and ointments for topical application, which are easy to administer and target specific affected areas. Our topical compounded preparations are used for infections (both fungal and bacterial), inflammations, local anesthetics and dental procedures. For otic compounded formulas we use a bioadhesive, thermoreversible gel. At cold temperatures it is liquid, and at room temperature it has the consistency of a gel.
In certain cases (e.g. thyroid disease), the veterinary patient needs a preparation that allows administration in the form of a transdermal gel. Typically, the transdermal gel is applied to the inside of the ear, and the treatment penetrates the skin into the systemic circulation.
If we are talking about a pet that does not accept oral treatment, transdermal gel may be the right alternative. Transdermal gels are packaged in special devices to simplify administration and accurately comply with the recommended dosage levels. The dose of active ingredient is usually integrated into a minimum amount of gel to facilitate the application of the compounded treatment.
Depending on the particularities of each patient, Crisia Pharmacy offers complete instructions on the use of the dosing applicator when dispensing the compounded preparation.
When an animal's health condition requires treatment with a dosage form with tissue adhesion, especially in the case of otic solutions, the option of using Crisia Farm thermoreversible gels represents an innovative solution. Veterinarians are often faced with the situation where after applying the otic solution, the patient tends to shake off and remove the treatment, but with the thermoreversible gel, it remains in the desired area.
The thermoreversible gel is easily conditioned as a liquid at 2-8 degrees Celsius, that will turn into a gel at body temperature within 5-6 seconds of application. The result is a preparation that can remain on the treated area for a longer period of time. These types of treatment are available in syringes with precise dosage.
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