Dermatitis herpetiformis
Dermatitis herpetiformis
- cutaneous manifestation of gluten intolerance -
Dermatitis herpetiformis is a chronic skin disease, most often associated with celiac disease. It is characterized by the appearance of itchy rashes and small blisters, similar to those of herpes infection – hence the name, although it is not related to herpes viruses.
How does dermatitis herpetiformis manifest?
Typical symptoms include:
- intense itching and burning sensation
- small grouped vesicles or red papules
- lesions frequently located on the elbows, knees, buttocks, scalp, or back
- excoriations and scabs caused by scratching
Why does dermatitis herpetiformis occur?
The condition is considered a cutaneous manifestation of gluten intolerance, being closely linked to celiac disease. In genetically predisposed patients, gluten ingestion triggers an immune response that affects both the small intestine and the skin.
Therapeutic options
Treatment aims to both control skin symptoms and manage the underlying cause.
Strict gluten-free diet represents the basic measure, with an essential role in preventing recurrences and long-term improvement. In acute phases, the doctor may recommend systemic medications (such as dapsone) to reduce inflammation and itching. As an adjunct, prescription-only medications may be used topical magistral preparations what can contain:
Alternative anti-inflammatory/antipruritic substances:
- resorcinol (in low concentrations, with keratolytic and antipruritic effect)
- ichthyol (ichthammol) – with mild anti-inflammatory and antiseptic effect, good for chronic itchy lesions
- witch hazel (extract or distillate) – with a calming, anti-inflammatory and slightly astringent effect
- menthol (in low concentrations, <1%) – for a cooling and soothing sensation on itching
Alternative healing and repairing substances:
- bismuth oxide (calming, anti-inflammatory)
- copper and zinc gluconate (in combination, for regenerating and antimicrobial effect)
- aloe vera extract (with a calming and repairing effect, in gel form)
Other emollients and protective agents:
- anhydrous lanolin (classic deep emollient)
- sweet almond oil or jojoba oil (natural emollient and soothing base)
- hydrolyzed collagen (supports skin regeneration)
You can see some examples here
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