Diabetic Neuropathy
Diabetic Neuropathy
- early signs of nerve damage caused by diabetes -
Diabetic neuropathy is a complication of diabetes that affects the peripheral nerves, causing pain, tingling, or numbness, particularly in the lower limbs.
How does it manifest itself?
Symptoms may include:
- stabbing or burning pain
- a tingling sensation
- numbness and localized hypersensitivity
Causes and Mechanism
Chronic hyperglycemia can damage the peripheral nerves and the small blood vessels that supply them.
Inflammation and oxidative stress also contribute to the deterioration of nerve fibers and the development of symptoms.
Inflammation and oxidative stress also contribute to the deterioration of nerve fibers and the development of symptoms.
Therapeutic solutions
Compounded preparations for diabetic neuropathy may include:
- creams or gels containing soothing and anti-inflammatory agentslidocaine, panthenol, and bisabolol
- local emollients to protect fragile skin: glycerin and ceramides
- active ingredients used to manage neuropathic pain:gabapentin, amitriptyline, and baclofen
- vehicles specially adapted for topical application,without fragrances or potentially irritating preservatives
You can find examples of recommended compounded treatments here. here
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